Cancer Awareness Month
National Cancer Survival Month
|We Asked a Caregiver: Cindy Mandarino|
|CC:Report is proud to present the second installment of our regular feature highlighting a caregiver working at the GRU Cancer Center. Read more…
|Amoush, PhD, DABR, Instructor, Department of Radiation Oncology|
|GRU to host National Library of Medicine course in biomedical informatics|
|The National Library of Medicine has awarded the Georgia Regents University Robert B. Greenblatt, M.D. Library a multi-year, $1.7 million contract to host its Biomedical Informatics Course. Read more…|
|Notable Upcoming Conferences & Symposia|
|Review these quick links to upcoming conferences that may be of particular interest. Read more…|
|Promotion & Tenure|
|Congratulations to those promoted and awarded tenure in 2014! Read more…|
|Congratulations to Dr. Colin (Ye) Huang, a specialist in Therapeutic Medical Physics, for passing the American Board of Radiology.|
|PGA Social Hour|
|The GRU Cancer Center Postdoctoral Graduate Association is hosting a PGA Social Hour. Come join us at Mi Rancho’s in Downtown Augusta (2 8th St, Augusta, GA 30901), Friday, June 13th at 6pm.
|Care means more than medicine: Serving the Survivor
“The good physician treats the disease. The great physician treats the patient who has the disease.”— Sir William Osler
How do we define the care we provide? What is, as a Cancer Center, our responsibility in terms of treatment? While the answer may seem easy, that we are charged with managing care and welfare through every step of the patient’s experience at the Cancer Center, the reality is deeper and much more significant.
Treating cancer is not about treating a disease. It’s about treating a patient. And while the medical aspect is certainly a primary piece of our purpose, it’s important to remember that addressing a patient’s health also means addressing their well-being. Cancer affects people. It affects the ways they approach their life both during and after treatment. For us to offer them a hearty handshake and farewell at the door when treatment is complete is tantamount to doing half a job. Our responsibility lasts much longer. We treat patients, but we also, quite happily, are increasingly called on to help survivors find their footing in a post-treatment world.
Have you Heard…?
- Employee Picnic Offers Fun in the Sun
In appreciation for the extraordinary work of everyone here, the GRU Cancer Center will be hosted an employee picnic June 5th in the “Secret Garden.” >> Continue reading
- Cancer Center’s Community Advisory Board Gets an Inside Look
On Wednesday, June 4, the GRU Cancer Center hosted a private tour and reception for the Cancer Center’s Community Advisory Board members…to show local decision makers the facilities and explain how they are used, as well as introduce them to the scientists, doctors and healthcare professionals that are working to build the GRU Cancer Center into something extraordinary… >> Continue reading
- Faculty Honored at 2014 Investiture Ceremony
The Investiture Ceremony is among the oldest of traditions in academia… Today this ceremony marks a celebration of those esteemed faculty members who have become honored and constant representatives of the University and members of the University family. >> Continue reading
- Sowing and Reaping with Seed Money
The internal development awards program of the GRU Cancer Center announced the recipients of its first themed opportunity – for collaborative research – two years ago this month….The Cancer Center has issued a total of six funding opportunities, including a current one supporting joint cancer research projects with the University of Georgia (UGA) Cancer Center, with winners to be announced later this summer. >> Continue reading
- Adult Inpatient Units Implement barcode technology for safe medication administration
Patient safety has been a growing concern in healthcare since the Institute of Medicine published their now infamous To Err Is Human: Building a Safer Health System report in November 1999. >> Continue reading
- Celis to Representing AACR in Tweet Chat on The Promise of Immunotherapy
Esteban Celis, MD, PhD, member, AACR Cancer Immunology Steering Committee, and professor of medicine at the GRU Cancer Center, will represent the AACR on this Twitter chat, which will be moderated by Time magazine’s senior health reporter Alice Park.>> Continue reading
- Huidong Shi, PhD, received a 2-year, $361K R21 grant from NIH/NCI for “Epigenetic regulation of T-cell dysfunction in chronic lymphocytic leukemia.”Project Narrative:Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the US, and it remains incurable. Half of CLL patients die not from CLL per se, but from disease-induced immune dysfunction and subsequent infections. As seen with CLL leukemic cells, the enzyme indoleamine 2,3-dioxygenase (IDO) can induce a state of immunosuppression that causes increased susceptibility to infections and failure of anti-tumor immune responses. IDO inhibitors are currently in clinical studies, as an attempt to rectify immune function in CLL patients. Dr. Shi’s group aims to determine epigenetic alterations in immune cell dysfunction in CLL and to identify biomarkers associated with clinical responses to the IDO inhibitor 1-MT. This translational research will study samples collected from an investigator-initiated, open-label, phase I/II trial of 1-MT in relapsed/refractory CLL patients. The overall goal is to understand molecular mechanisms responsible for CLL immune dysfunction and to promote the development of effective immunotherapy against the disease.
- Theodore S. Johnson, MD, PhD, received an NIH R13 Research Conference Grant in the amount of $6500 to support the “Career Development and Increasing Diversity in Pediatric Hematology/Oncology” conference, which occurred May 14-17, 2014 in Chicago.Project Narrative: Ethnic minorities, women, and other diversity groups are under-represented in leadership positions for medical specialties and pediatric subspecialties, including Pediatric Hematology/Oncology. Working together, the American Society of Pediatric Hematology/Oncology (ASPHO) leadership and general membership are using a variety of approaches to advance diversity issues within ASPHO. This R13 supported a diversity-oriented workshop during the 2014 ASPHO annual meeting to develop Strategies for Increasing Workforce Diversity in Pediatric Hematology/Oncology and address the barriers to entry and advancement for trainees and professionals with diverse backgrounds so that they can become successful leaders. A key addition to this year’s workshop was the expansion of trainee travel awards to include sponsorship of not only fellowship trainees with diverse backgrounds, but also under-represented junior trainees (medical students and residents) who were paired with faculty “guides.” These guides helped ensure that the sponsored trainees were able to optimize their conference experience. Guides also provided point-of-contact and mentorship within the field of Pediatric Hematology/Oncology as trainees begin to make career development plans following the conference.
- Ghuman MS, Woodall MN, Alleyne CH Jr. Teaching NeuroImages: Microvascular decompression of the optic nerve. Neurology. 2014 May 20;82(20):1847. doi: 10.1212/01.wnl.0000450225.45489.9b. No abstract available.
- Pye C, Elsherbiny NM, Ibrahim AS, Liou GI, Chadli A, Al-Shabrawey M, Elmarakby AA. Adenosine Kinase Inhibition Protects The Kidney Against Streptozotocin-Induced Diabetes Through Anti-inflammatory and Anti-oxidant Mechanisms. Pharmacol Res. 2014 May 16. pii: S1043-6618(14)00063-2. doi: 10.1016/j.phrs.2014.05.004. [Epub ahead of print]
- Bailey LJ, Choudhary V, Merai P, Bollag WB. Preparation of Primary Cultures of Mouse Epidermal Keratinocytes and the Measurement of Phospholipase D Activity. Methods Mol Biol. 2014 May 20. [Epub ahead of print]
- Lee YY, Erdogan A, Rao SS. How to assess regional and whole gut transit time with wireless motility capsule. J Neurogastroenterol Motil. 2014 Apr 30;20(2):265-70. doi: 10.5056/jnm.2014.20.2.265.
- Barik A, Zhang B, Sohal GS, Xiong WC, Mei L. Interaction between Agrin and Wnt signalings in development of vertebrate neuromuscular junction. Dev Neurobiol. 2014 May 17. doi: 10.1002/dneu.22190. [Epub ahead of print] No abstract available.
- Sierra RA, Thevenot P, Raber P, Cui Y, Parsons C, Ochoa AC, Trillo-Tinoco J, Del Valle L, Rodriguez PC. Rescue of Notch 1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T cell suppression and enhances immunotherapy in cancer. Cancer Immunol Res. 2014 May 15. pii: canimm.0021.2014. [Epub ahead of print]
- Ranganathan P, Jayakumar C, Mohamed R, Weintraub NL, Ramesh G. Semaphorin 3A inactivation suppresses ischemia/reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol. 2014 May 14. pii: ajprenal.00177.2014. [Epub ahead of print]
- Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM. Monomethylfumarate Induces Fetal Hemoglobin Production in Cultured Human Retinal Pigment Epithelial (RPE) and Erythroid Cells, and in Intact Retina. Invest Ophthalmol Vis Sci. 2014 May 13. pii: IOVS-14-14179. doi: 10.1167/iovs.14-14179. [Epub ahead of print]
- Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, Soiffer RJ, Antin JH, Ritz J, Dubovsky JA, Byrd JC, Macdonald KP, Hill GR, Blazar BR. Increased T follicular helper cells and germinal center B cells are required for chronic GVHD (cGVHD) and bronchiolitis obliterans. Blood. 2014 May 12. [Epub ahead of print]
- Terry AV Jr, Callahan PM, Beck WD, Vandenhuerk L, Sinha S, Bouchard K, Schade R, Waller JL. Repeated exposures to diisopropylfluorophosphate result in impairments of sustained attention and persistent alterations of inhibitory response control in rats. Neurotoxicol Teratol. 2014 May 10. pii: S0892-0362(14)00108-1. doi: 10.1016/j.ntt.2014.04.069. [Epub ahead of print]
- Rao SS, Coss-Adame E, Tantiphlachiva K, Attaluri A, Remes-Troche J. Translumbar and transsacral magnetic neurostimulation for the assessment of neuropathy in fecal incontinence. Dis Colon Rectum. 2014 May;57(5):645-52. doi: 10.1097/DCR.0000000000000069.
- Tawfik A, Gnana-Prakasam JP, Smith SB, Ganapathy V. Deletion of Hemojuvelin, an Iron-regulatory Protein, in Mice Results in Abnormal Angiogenesis and Vasculogenesis in Retina along with Reactive Gliosis. Invest Ophthalmol Vis Sci. 2014 May 8. pii: iovs.13-13677v1. doi: 10.1167/iovs.13-13677. [Epub ahead of print]
- Bozec A, Zaiss MM, Kagwiria R, Voll R, Rauh M, Chen Z, Mueller-Schmucker S, Kroczek RA, Heinzerling L, Moser M, Mellor AL, David JP, Schett G. T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway. Sci Transl Med. 2014 May 7;6(235):235ra60. doi: 10.1126/scitranslmed.3007764.
- Lemos H, Huang L, Chandler PR, Mohamed E, Souza GR, Li L, Pacholczyk G, Barber GN, Hayakawa Y, Munn DH, Mellor AL. Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis. J Immunol. 2014 May 5. [Epub ahead of print]
- Jin C, O’Boyle S, Kleven DT, Pollock JS, Pollock DM, White JJ. Anti-hypertensive and anti-inflammatory actions of combined azilsartan and chlorthalidone in Dahl salt-sensitive rats on a high-fat, high-salt diet. Clin Exp Pharmacol Physiol. 2014 May 6. doi: 10.1111/1440-1681.12250. [Epub ahead of print]
- Schaeffer DJ, Krafft CE, Schwarz NF, Chi L, Rodrigue AL, Pierce JE, Allison JD, Yanasak NE, Liu T, Davis CL, McDowell JE. An 8-month exercise intervention alters frontotemporal white matter integrity in overweight children. Psychophysiology. 2014 May 5. doi: 10.1111/psyp.12227. [Epub ahead of print]
- Gnana-Prakasam JP, Baldowski RB, Ananth S, Martin PM, Smith SB, Ganapathy V. Retinal expression of the serine protease matriptase-2 (Tmprss6) and its role in retinal iron homeostasis. Mol Vis. 2014 Apr 26;20:561-74. eCollection 2014
- Condamine T, Kumar V, Ramachandran IR, Youn JI, Celis E, Finnberg N, El-Deiry WS, Winograd R, Vonderheide RH, English NR, Knight SC, Yagita H, McCaffrey JC, Antonia S, Hockstein N, Witt R, Masters G, Bauer T, Gabrilovich DI. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014 May 1. pii: 74056. doi: 10.1172/JCI74056. [Epub ahead of print]
- Pimentel M, Chang C, Chua KS, Mirocha J, Dibaise J, Rao S, Amichai M. Antibiotic Treatment of Constipation-Predominant Irritable Bowel Syndrome. Dig Dis Sci. 2014 May 1. [Epub ahead of print]
- Jones MC, Rueggeberg FA, Faircloth HA, Cunningham AJ, Bush CM, Prosser JD, Waller JL, Postma GN, Weinberger PM. Defining the biomechanical properties of the rabbit trachea. Laryngoscope. 2014 Apr 29. doi: 10.1002/lary.24739. [Epub ahead of print]
- Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T cell responses through the PD-1/PD-L1 axis. Cancer Res. 2014 Apr 29. [Epub ahead of print]
- Viazzi F, Ramesh G, Jayakumar C, Leoncini G, Garneri D, Pontremoli R. Increased urine semaphorin-3A is associated with renal damage in hypertensive patients with chronic kidney disease: a nested case-control study. J Nephrol. 2014 Apr 23. [Epub ahead of print]
- Paul A, Garcia YA, Zierer BK, Patwardhan C, Gutierrez O, Hildenbrand Z, Harris DC, Balsiger HA, Sivils JC, Johnson JL, Buchner J, Chadli A, Cox MB. The Cochaperone SGTA (Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha) Demonstrates Regulatory Specificity for the Androgen, Glucocorticoid and Progesterone Receptors. J Biol Chem. 2014 Apr 27. [Epub ahead of print]
- Merchen TD, Boesen EI, Gardner JR, Harbarger R, Kitamura E, Mellor A, Pollock DM, Ghaffari A, Podolsky R, Nahman NS Jr. Indoleamine 2,3-dioxygenase inhibition alters the non-coding RNA transcriptome following renal ischemia-reperfusion injury. Transpl Immunol. 2014 May;30(4):140-4. doi: 10.1016/j.trim.2014.04.003. Epub 2014 Apr 18.
- Meng X, Frey K, Matuszak M, Paul S, Ten Haken R, Yu J, Kong FM. Changes in functional lung regions during the course of radiation therapy and their potential impact on lung dosimetry for non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):145-51. doi: 10.1016/j.ijrobp.2014.01.044.
- Chen X, Wang X, Ruan A, Han W, Zhao Y, Lu X, Xiao P, Shi H, Wang R, Chen L, Chen S, Du Q, Yang H, Zhang X. miR-141 Is a Key Regulator of Renal Cell Carcinoma Proliferation and Metastasis by Controlling EphA2 Expression. Clin Cancer Res. 2014 May 15;20(10):2617-30. doi: 10.1158/1078-0432.CCR-13-3224. Epub 2014 Mar 19.
- Kumai T, Ishibashi K, Oikawa K, Matsuda Y, Aoki N, Kimura S, Hayashi S, Kitada M, Harabuchi Y, Celis E, Kobayashi H. Induction of tumor-reactive T helper responses by a posttranslational modified epitope from tumor protein p53. Cancer Immunol Immunother. 2014 May;63(5):469-78. doi: 10.1007/s00262-014-1533-z. Epub 2014 Mar 15.
- Choudhary V, Kaddour-Djebbar I, Alaisami R, Kumar MV, Bollag WB. Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells. Int J Oncol. 2014 May;44(5):1767-73. doi: 10.3892/ijo.2014.2343. Epub 2014 Mar 13.
- Takemori T, Kaji T, Takahashi Y, Shimoda M, Rajewsky K. Generation of memory B cells inside and outside germinal centers. Eur J Immunol. 2014 May;44(5):1258-64. doi: 10.1002/eji.201343716. Epub 2014 Apr 10.
- Thangjam GS, Dimitropoulou C, Joshi AD, Barabutis N, Shaw MC, Kovalenkov Y, Wallace CM, Fulton DJ, Patel V, Catravas JD. Novel Mechanism of Attenuation of LPS-Induced NF-κB Activation by the Heat Shock Protein 90 Inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in Human Lung Microvascular Endothelial Cells. Am J Respir Cell Mol Biol. 2014 May;50(5):942-52. doi: 10.1165/rcmb.2013-0214OC.
- Fahmy CE, Carrau R, Kirsch C, Meeks D, de Lara D, Solares CA, Otto BA, Prevedello DM. Volumetric analysis of endoscopic and traditional surgical approaches to the infratemporal fossa. Laryngoscope. 2014 May;124(5):1090-6. doi: 10.1002/lary.24428. Epub 2013 Oct 29.
- Orme-Johnson DW, Barnes VA. Effects of the transcendental meditation technique on trait anxiety: a meta-analysis of randomized controlled trials. J Altern Complement Med. 2014 May;20(5):330-41. doi: 10.1089/acm.2013.0204. Epub 2013 Oct 9.
- Oh JS, Bhalla VK, Needham L, Sharma S, Pipkin WL, Hatley RM, Howell CG. Müllerian-type, cutaneous ciliated cyst in the gluteal cleft mimicking a pilonidal cyst. Pediatr Surg Int. 2014 May;30(5):545-8. doi: 10.1007/s00383-013-3363-z. Epub 2013 Aug 4.
- Sharma BK, Patil M, Ande S. Negative regulators of brown adipose tissue (BAT)-mediated thermogenesis. J Cell Physiol. Ahead of print. doi: 10.1002/jcp.24664