Nahid Mavechi, PhDThis research will study how heat shock transcription factor 1 (Hsf1) functions in the regulation of cell metabolism and inflammation, which are critical factors for malignant cell proliferation and liver cancer development. Results will provide rationale for developing novel preventive and therapeutic strategies for cancers, including hepatocellular carcinoma, that arise on the background of chronic hepatic injury due to impaired liver metabolism and proteostasis.
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