David H. Munn, MD, received an R01 subcontract from LSU Health System for $36K annually for “Metabolic approaches to treat severe viral and inflammatory diseases.” Justin Choi, PhD, received an R01 subcontract from Mayo Clinic for $24K annually for...
Citation Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA. MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes. PLoS Genet. 2013 Dec;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26...
CitationNagato T, Lee YR, Harabuchi Y, Celis E. Combinatorial Immunotherapy of Polyinosinic-Polycytidylic Acid and Blockade of Programmed Death-1 Induces Effective CD8 T Cell Responses against Established Tumors.Clin Cancer Res. 2014 Jan 3. [Epub...
Citation Blackburn AR 2nd, Hamrick MW, Chutkan N, Sangani R, Waller JL, Corpe R, Prasad PD, Isales CM, Ganapathy V, Fulzele S. Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues. BMC...
Citation Metz R, Smith C, Duhadaway JB, Chandler P, Baban B, Merlo LM, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, J Muller A, Prendergast GC. IDO2 is critical for IDO1-mediated T cell regulation and exerts a non-redundant function in...
Phase 3 Clinical Trial for Sickle Cell Disease: Betty Pace, MD, received a $178K, 2-year award from Mast Therapeutics, Inc. for “MST-188-01: Evaluation of Purified Poloxamer 188 in Children in Crisis (EPIC): A Phase 3 Randomized, Double blind...
Theodore S. Johnson, MD, PhD, received a $375K, 3-year award from Alex’s Lemonade Stand Foundation (ALSF) for “IDO-Based Immunotherapy for Pediatric Brain Tumors.” This is the first grant to be awarded to GRU/MCG by ALSF, a foundation devoted to...
Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer. Citation Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M...
A novel piperazine derivative potently induces caspase-dependent apoptosis of cancer cells via inhibition of multiple cancer signaling pathways. Citation She EX, Hao Z. A novel piperazine derivative potently induces caspase-dependent...
COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis. Citation Shao J, Teng Y, Padia R, Hong S, Noh H, Xie X, Mumm JS, Dong Z, Ding HF, Cowell J, Kim J, Han J, Huang S. COP1 and GSK3β Cooperate to...