Dr. John E. Janik and colleagues from the National Institutes of Health and from the Roger Williams Medical Center report in the Proceedings of the National Academy of Sciences on a novel radioimmunotherapy that generated responses in 50% of...
The laboratory of GRU Cancer Center’s Dr. Chunhong Yan is interested in the molecular mechanism behind the development of prostate cancer. Prostate cancer is associated with aging – not only the genetic alterations induced by the aging process, but...
It has long been established that genetic alterations leading to down-regulated expression of the tumor suppressor protein Pten characterize a major subtype of prostate cancer. As reported recently in Oncogene, the laboratory of GRU Cancer Center’s...
A report headed by GRU Cancer Center physician Martha K. Terris, MD, and published in the journal Cancer presents the first detailed evaluation of suicide associated with genitourinary cancer patients. The research studied a large sample size –...
Published in Oncotarget, researchers led by Dr. Shuang Huang have identified a currently available drug that may benefit a subset of ovarian cancer patients. Results of GRU Cancer Center’s Drs. Huang and Han-Fei Ding and their collaborators show...
A newly discovered, naturally occurring compound, verticillin A, may provide long-awaited improvement in treating metastatic colon cancer. Dr. Kebin Liu headed a study recently published in the Journal of Immunology, in which he and GRU Cancer...
Led by Dr. Chunhong Yan, Cancer Center researchers Drs. Liwei Lang and Han-Fei Ding and their colleagues have generated a novel strategy for identifying compounds that may be further developed as anti-cancer therapeutics. Since overexpression of...
In an innovative pair of papers published in Radiotherapy and Oncology from the laboratories of Drs. Jian-Yue Jin and Feng-Ming (Spring) Kong of the Georgia Regents University (GRU) Cancer Center, a new model using biomarkers to predict radiation...
Metabolic reprogramming – shifting from oxidative phosphorylation to aerobic glycolysis and glutaminolysis – provides a mechanism for cancer cells to meet the energy demands required to maintain increased proliferation and survival. Many cancer...
Clinical trials testing vaccine-mediated therapy against malignant melanoma have generated disappointing responses. The laboratory of Esteban Celis, MD, PhD, at the GRU Cancer Center proposes that this is due to an insufficient number of antigen...