Volume 1, Issue 2


	Chunhong Yan, Ph.D. Molecular Oncology and Biomarkers


Volume 1, Issue 1

An Ounce of Prevention…

“”The proximity of a desirable thing tempts one to overindulgence. On that path lies danger.” — Frank Herbert

With leftover Halloween candy still in a bowl by the door and the holiday season looming before us, it’s hard for us to imagine not being urged to belly up to a buffet for one more serving of whatever seasonal treat is on offer. I know I sometimes find it difficult to ignore the siren song of a sugar cookie. Still, it’s important to remember that there’s a difference between eating well and being well-fed. Read more >>

Have you Heard…?

Grant News

Extramural

Darren D. Browning, PhD, Biochemistry and Molecular Biology, received a 5-year, $1.8M R01 grant from NIH/NCI for “Colon cancer chemoprevention with phosphodiesterase-5 inhibitors.” Read more >>

Jian-Yue Jin, PhD, Radiation Oncology, received a 3-year, $1.2M R01 grant from NCI/NIH for “A synchronized moving grid (SMOG) system to improve CBCT for IGRT and ART.” Read more >>

Vadivel Ganapathy, PhD., Biochemistry and Molecular Biology, received a 3-year, $562,500 grant from the Department of Defense for Homocysteine Is an Oncometabolite in Breast Cancer, Which Promotes Tumor Progression and Metastasis. Read more >>

Newly Activated Clinical Trials

Sharad Ghamande, MD, received $158K from VentiRx Pharmaceuticals for “A randomized, double-blind, placebo-controlled phase II study of VTX 2337 in combination with pegylated liposomal doxorubicin (PLD) in patients with recurrent or persistent epithelial ovarian, fallopian tube, or primary peritoneal cancer.” Read more >>

Recent Publications

Blood Hematopoietic cell transplant:
Rapid donor T-cell engraftment increases the risk of chronic graft-versus-host disease following salvage allogeneic peripheral blood hematopoietic cell transplantation for bone marrow failure syndromes. Read more >>

Breast Cancer:
COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis. Read more >>

Breast Cancer:
Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer. Read more >>

Cancer signaling:
A novel piperazine derivative potently induces caspase-dependent apoptosis of cancer cells via inhibition of multiple cancer signaling pathways. Read more >>

Liver cancer:
Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma. Read more >>

Metastasis model:
Evaluating human cancer cell metastasis in zebrafish. Read more >>

Ovarian cancer:
Human Ovarian Cancer Stroma Contains Luteinized Theca Cells Harboring Tumor Suppressor Gene GT198 Mutations. Read more >>

Sequencing tool:
ESTclean: a cleaning tool for next-gen transcriptome shotgun sequencing. Read more >>

Announcements

Promote Your Career – Promote Cancer Care Read more >>

Keystone Announcements Read more >>

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