Researchers at the GRU Cancer Center have identified new molecular players and potential biomarkers in breast cancer tumorigenesis. A process known as epithelial-to-mesenchymal transition (EMT) represents changes in cancer cell characteristics that...
This work has gained national publicity, as indicated by the following reports: New potential options for attacking cancer stem cells in triple-negative breast cancer: New breakthrough for triple-negative breast cancer, Hispanic women to benefit?:...
Citation Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA. MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes. PLoS Genet. 2013 Dec;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26...
Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer. Citation Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M...
COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis. Citation Shao J, Teng Y, Padia R, Hong S, Noh H, Xie X, Mumm JS, Dong Z, Ding HF, Cowell J, Kim J, Han J, Huang S. COP1 and GSK3β Cooperate to...